Chemical Structure : IWR-1
CAS No.:
1127442-82-3
IWR-1
(endo-IWR1, IWR-1-endo, IWR1)
Catalog No. : PC-42926Not For Human Use, Lab Use Only.
IWR-1 is a potent inhibitor of Wnt signaling with EC50 of 0.2 uM.
Packing Price Stock Quantity 10 mg $68 In stock 0 1 2 3 4 5 25 mg $108 In stock 0 1 2 3 4 5 50 mg $178 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4292601
Biological Activity
IWR-1 is a potent inhibitor of Wnt signaling with EC50 of 0.2 uM.
Physicochemical Properties
M.Wt
409.4366
Formula
C25H19N3O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 46 mg/mL
Chemical Name/SMILES
Benzamide, 4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinyl-, rel-
References
1. Lu J, et al. Bioorg Med Chem Lett.
2. Narwal M, et al. J Med Chem
3. Kulak O, et al. Mol Cell Biol
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