Chemical Structure : Ibutamoren mesylate
CAS No.: 159752-10-0
Catalog No.: PC-45866Not For Human Use, Lab Use Only.
Ibutamoren mesylate (MK-0677) is a non-peptidic, poten and selective, orally-active agonist of the ghrelin receptor (GHSR) with EC50 of 1.3 nM (releases GH from rat pituitary cells).
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10 mg | $58 | In stock | |
25 mg | $98 | In stock | |
50 mg | $158 | In stock | |
100 mg | $228 | In stock | |
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Ibutamoren mesylate (MK-0677) is a non-peptidic, poten and selective, orally-active agonist of the ghrelin receptor (GHSR) with EC50 of 1.3 nM (releases GH from rat pituitary cells).
Ibutamoren mesylate (MK-0677) significantly increased peak GH concentrations 20.4-fold at 0.25 mg/kg in beagles.
Ibutamoren mesylate (MK-0677) has shown to sustain activation of GH-IGF-1 Axis and increase in lean body mass but no change in total fat mass or visceral fat.
M.Wt | 624.7692 | |
Formula | C28H40N4O8S2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Propanamide, 2-amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4'-piperidin]-1'-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methyl-, methanesulfonate (1:1) |
1. Patchett AA, et al. Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):7001-5.
2. Jacks T, et al. Endocrinology. 1996 Dec;137(12):5284-9.
3. Copinschi G, et al. Neuroendocrinology. 1997 Oct;66(4):278-86.
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