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Iclaprim

Chemical Structure : Iclaprim

CAS No.: 192314-93-5

Iclaprim (AR-100)

Catalog No.: PC-23224Not For Human Use, Lab Use Only.

Iclaprim (AR-100) is a selective dihydrofolate reductase (DHFR) inhibitor, is active against methicillin, TMP and vancomycin resistant strains, has MIC90 of 0.5 ug/mL against C. trachomatis and C. pneumoniae.

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Biological Activity

Iclaprim (AR-100) is a selective dihydrofolate reductase (DHFR) inhibitor, is active against methicillin, TMP and vancomycin resistant strains, has MIC90 of 0.5 ug/mL against C. trachomatis and C. pneumoniae.

Physicochemical Properties

M.Wt 354.41
Formula C19H22N4O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-((2-Cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)methyl)pyrimidine-2,4-diamine

References

1. Kohlhoff SA, et al. Antimicrob Agents Chemother. 2004 May;48(5):1885-6.

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