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Idroxioleic acid

Chemical Structure : Idroxioleic acid

CAS No.: 56472-29-8

Idroxioleic acid (2-OHOA, (Rac)-Idroxioleic acid)

Catalog No.: PC-22903Not For Human Use, Lab Use Only.

Idroxioleic acid (2-OHOA) is a first-in-class brain-penetrating synthetic hydroxylated lipid, activates sphingomyelin synthase (SMS) expression and regulates membrane-lipid composition and mitochondrial energy production, inducing cancer cell autophagy.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Idroxioleic acid (2-OHOA) is a first-in-class brain-penetrating synthetic hydroxylated lipid, activates sphingomyelin synthase (SMS) expression and regulates membrane-lipid composition and mitochondrial energy production, inducing cancer cell autophagy.

Physicochemical Properties

M.Wt 298.47
Formula C18H34O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(Z)-2-Hydroxyoctadec-9-enoic acid

References

1. Juanita Lopez, et al. Br J Cancer. 2023 Sep;129(5):811-818.

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