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Ifenprodil tartrate

Chemical Structure : Ifenprodil tartrate

CAS No.: 23210-58-4

Ifenprodil tartrate (Ifenprodil hemitartrate)

Catalog No.: PC-43280Not For Human Use, Lab Use Only.

Ifenprodil tartrate is a potent, GluN2B-specific inhibitor NMDA receptor antagonist, specifically targets NR1A/NR2B receptors with IC50 of 0.34 uM, 400-fold selective over NR1A/NR2A receptors.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Ifenprodil tartrate is a potent, GluN2B-specific inhibitor NMDA receptor antagonist, specifically targets NR1A/NR2B receptors with IC50 of 0.34 uM, 400-fold selective over NR1A/NR2A receptors.
Ifenprodil tartrate also inhibits GIRK channels, and interacts with alpha1 adrenergic, serotonin, and sigma receptors.

Physicochemical Properties

M.Wt 400.49
Formula C21H27NO2 . 1/2C4H6O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 500 mg/mL

Chemical Name/SMILES

1-Piperidineethanol, α-(4-hydroxyphenyl)-β-methyl-4-(phenylmethyl)-, (2R,3R)-2,3-dihydroxybutanedioate (2:1)

References

1. Korinek M, et al. Steroids. 2011 Dec 11;76(13):1409-18.

2. Kobayashi T, et al. Neuropsychopharmacology. 2006 Mar;31(3):516-24.

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