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Ilaprazole

Chemical Structure : Ilaprazole

CAS No.: 172152-36-2

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Ilaprazole (IY81149;IY-81149;IY 81149)

Catalog No.: PC-42413Not For Human Use, Lab Use Only.

A potent, orally active proton pump inhibitor that irreversibly inhibits H+/K(+)-ATPase with IC50 of 6 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A potent, orally active proton pump inhibitor that irreversibly inhibits H+/K(+)-ATPase with IC50 of 6 uM; dose-dependently increases gastric pH in anesthetized rats, exhibits superior potency against gastric acid secretion compared with omeprazole.

Ulcer

Approved

Physicochemical Properties

M.Wt 366.43682
Formula C19H18N4O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 35 mg/mL
Chemical Name/SMILES

1H-Benzimidazole, 2-[[(4-methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-6-(1H-pyrrol-1-yl)-

References

1. Kim EJ, et al. Arzneimittelforschung. 2001 Jan;51(1):51-9.

2. Kwon D, et al. Arzneimittelforschung. 2001;51(3):204-13.

3. Seo KA, et al. Xenobiotica. 2012 Mar;42(3):278-84.

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