Ilaprazole |CAS:172152-36-2 Probechem Biochemicals

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Chemical Structure : Ilaprazole

Ilaprazole (IY81149;IY-81149;IY 81149)

Catalog No.: PC-42413Not For Human Use, Lab Use Only.

A potent, orally active proton pump inhibitor that irreversibly inhibits H+/K(+)-ATPase with IC50 of 6 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A potent, orally active proton pump inhibitor that irreversibly inhibits H+/K(+)-ATPase with IC50 of 6 uM; dose-dependently increases gastric pH in anesthetized rats, exhibits superior potency against gastric acid secretion compared with omeprazole.

Ulcer

Approved

Physicochemical Properties

M.Wt	366.43682
Formula	C19H18N4O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 35 mg/mL
Chemical Name/SMILES	1H-Benzimidazole, 2-[[(4-methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-6-(1H-pyrrol-1-yl)-

References

1. Kim EJ, et al. Arzneimittelforschung. 2001 Jan;51(1):51-9.

2. Kwon D, et al. Arzneimittelforschung. 2001;51(3):204-13.

3. Seo KA, et al. Xenobiotica. 2012 Mar;42(3):278-84.

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Ilaprazole (IY81149;IY-81149;IY 81149)

Biological Activity

Physicochemical Properties

References

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