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Imagabalin

Chemical Structure : Imagabalin

CAS No.: 610300-07-7

Imagabalin (PD 0332334, PD 332334)

Catalog No.: PC-61833Not For Human Use, Lab Use Only.

Imagabalin (PD 0332334) is a novel ligand for the α2δ subunit of the voltage-dependent calcium channel (VDCC) with some selectivity for the α2δ1 subunit over α2δ2.

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    Biological Activity

    Imagabalin (PD 0332334) is a novel ligand for the α2δ subunit of the voltage-dependent calcium channel (VDCC) with some selectivity for the α2δ1 subunit over α2δ2.
    Imagabalin demonstrated preclinical efficacy of anxiolytic, analgesic, hypnotic, and anticonvulsant-like activity for the treatment of generalized anxiety disorder.

    Physicochemical Properties

    M.Wt 173.253
    Formula C9H19NO2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (3S,5R)-3-amino-5-methyloctanoic acid

    References

    1. Quintero JE, et al. Brain Res. 2011 Jul 15;1401:1-9.

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