Imagabalin hydrochloride |CAS:610300-00-0 Probechem Biochemicals

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Chemical Structure : Imagabalin hydrochloride

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Imagabalin hydrochloride (PD-0332334;PD-332334)

Catalog No.: PC-61834Not For Human Use, Lab Use Only.

Imagabalin (PD 0332334) is a novel ligand for the α2δ subunit of the voltage-dependent calcium channel (VDCC) with some selectivity for the α2δ1 subunit over α2δ2.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Imagabalin (PD 0332334) is a novel ligand for the α2δ subunit of the voltage-dependent calcium channel (VDCC) with some selectivity for the α2δ1 subunit over α2δ2; demonstrated preclinical efficacy of anxiolytic, analgesic, hypnotic, and anticonvulsant-like activity for the treatment of generalized anxiety disorder.

Anxiety

Phase 3 Discontinued

Physicochemical Properties

M.Wt	209.714
Formula	C9H20ClNO2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(3S,5R)-3-amino-5-methyloctanoic acid hydrochloride

References

1. Quintero JE, et al. Brain Res. 2011 Jul 15;1401:1-9.

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Imagabalin hydrochloride (PD-0332334;PD-332334)

Biological Activity

Physicochemical Properties

References

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