Chemical Structure : Indimitecan
CAS No.: 915360-05-3
Catalog No.: PC-63535Not For Human Use, Lab Use Only.
Indimitecan (LMP776, NSC 725776) is an anticancer DNA Topoisomerase I (Top1) inhibitor, shows antiproliferative activities against various human cancer cell lines.
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Indimitecan (LMP776, NSC 725776) is an anticancer DNA Topoisomerase I (Top1) inhibitor, shows antiproliferative activities against various human cancer cell lines.
M.Wt | 459.458 | |
Formula | C25H21N3O6 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
6-[3-(1H-Imidazol-1-yl)propyl]-2,3-dimethoxy-5H-[1,3]dioxolo[4',5':5,6]indeno[1,2-c]isoquinoline-5,12(6H)-dione |
1. Cinelli MA, et al. J Med Chem. 2012 Dec 27;55(24):10844-62.
2. Maede Y, et al. Mol Cancer Ther. 2014 Jan;13(1):214-20.
3. Beck DE, et al. J Med Chem. 2014 Feb 27;57(4):1495-512.
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