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Indirubin

Chemical Structure : Indirubin

CAS No.: 479-41-4

Indirubin (Couroupitine B, Indigo red)

Catalog No.: PC-23914Not For Human Use, Lab Use Only.

Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against CML, is a high affinity ligand of aryl hydrocarbon receptor (AHR) with dissociation constant (KD) value of 46.6 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against CML, is a high affinity ligand of aryl hydrocarbon receptor (AHR) with dissociation constant (KD) value of 46.6 nM.

Physicochemical Properties

M.Wt 262.27
Formula C16H10N2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

[2,3'-Biindolinylidene]-2',3-dione

References

1. Diao X, et al. Nat Commun. 2025 Feb 3;16(1):1282.

2. Kim MH, et al. J Ethnopharmacol. 2013 Jan 9;145(1):214-9.

3. Hsieh WL, et al. J Dermatol Sci. 2012 Aug;67(2):140-6.

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