Indomethacin | COX1/2 inhibitor, AKR1C3 inhibitor

Chemical Structure : Indomethacin

CAS No.: 53-86-1

Indomethacin (Indometacin)

Catalog No.: PC-24480Not For Human Use, Lab Use Only.

Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC50 of 18/26 nM respectively, also is an effective and selective AKR1C3 inhibitor (IC50=0.1 uM).

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500 mg	$28	In stock
1 g	$38	In stock
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Biological Activity

Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC50 of 18/26 nM respectively, also is an effective and selective AKR1C3 inhibitor (IC50=0.1 uM).

Physicochemical Properties

M.Wt	357.79
Formula	C19H16ClNO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid

References

1. Riendeau D, et, al. Br J Pharmacol. 1997 May;121(1):105-17.

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Indomethacin (Indometacin)

Biological Activity

Physicochemical Properties

References

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