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Chemical Structure : Indotecan
CAS No.: 915303-09-2
Catalog No.: PC-63536Not For Human Use, Lab Use Only.
Indotecan (LMP400) is an anticancer DNA Topoisomerase I (Top1) inhibitor, inhibits P388, HCT116, MCF-7 cell lines with IC50 of 300, 1200, 560 nM respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $138 | In stock | |
| 10 mg | $218 | In stock | |
| 25 mg | $358 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Indotecan (LMP400) is an anticancer DNA Topoisomerase I (Top1) inhibitor, inhibits P388, HCT116, MCF-7 cell lines with IC50 of 300, 1200, 560 nM respectively.
| M.Wt | 478.501 | |
| Formula | C26H26N2O7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2,3-Dimethoxy-6-[3-(4-morpholinyl)propyl]-5H-[1,3]dioxolo[4',5':5,6]indeno[1,2-c]isoquinoline-5,12(6H)-dione |
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1. Cinelli MA, et al. J Med Chem. 2012 Dec 27;55(24):10844-62.
2. Maede Y, et al. Mol Cancer Ther. 2014 Jan;13(1):214-20.
3. Beck DE, et al. J Med Chem. 2014 Feb 27;57(4):1495-512.
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