Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Indoximod
CAS No.: 110117-83-4
Catalog No.: PC-45061Not For Human Use, Lab Use Only.
Indoximod (NLG-8189, 1-Methyl-D-tryptophan, D-1MT) is a potent Indoleamine 2,3-dioxygenase (IDO) inhibitor with IC50 of 7 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 250 mg | $38 | In stock | |
| 1 g | $68 | In stock | |
| 5 g | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Indoximod (NLG-8189, 1-Methyl-D-tryptophan, D-1MT) is a potent Indoleamine 2,3-dioxygenase (IDO) inhibitor with IC50 of 7 uM.
Indoximod prevents T-cell anergy triggered by dendritic cells overexpressing IDO in mice.
Indoximod augments the antitumor and antiviral immunoresponse of CD8+ T-cells and reduces tumor volume in mice with xenografts overexpressing IDO.
| M.Wt | 218.2518 | |
| Formula | C12H14N2O2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
DMSO: 0.55 mg/mL (Need ultrasonic and warming); H2O: 6.2 mg/mL (Need ultrasonic, warming and concentrated HCl) |
|
| Chemical Name/SMILES |
D-Tryptophan, 1-methyl- |
|
1. Dolušić E, et al. Eur J Med Chem. 2011 Jul;46(7):3058-65.
2. Qian F, et al. Cancer Res. 2009 Jul 1;69(13):5498-504.
3. Metz R, et al. Cancer Res. 2007 Aug 1;67(15):7082-7.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
