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Iperoxo

Chemical Structure : Iperoxo

CAS No.: 247079-84-1

Iperoxo (mAChR agonist Iperoxo)

Catalog No.: PC-60327Not For Human Use, Lab Use Only.

Iperoxo is an extremely potent muscarinic receptor agonist with EC50 of 2.12 nM and 8.47 nM for M2 and M4, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Iperoxo is an extremely potent muscarinic receptor agonist with EC50 of 2.12 nM and 8.47 nM for M2 and M4, respectively.
Iperoxo significantly exceeds ACh in Gi /Gs signalling competence CHO-hM2 cells.

Physicochemical Properties

M.Wt 324.16
Formula C10H17IN2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-[(4,5-Dihydro-3-isoxazolyl)oxy]-N,N,N-trimethyl-2-butyn-1-aminium iodide

References

1. Schrage R, et al. Br J Pharmacol. 2013 May;169(2):357-70.

2. Kruse AC, et al. Nature. 2013 Dec 5;504(7478):101-6.

3. Croy CH, et al. Mol Pharmacol. 2014 Jul;86(1):106-15.

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