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Ipidacrine

Chemical Structure : Ipidacrine

CAS No.: 118499-70-0

Ipidacrine (Amiridine, NIK 247)

Catalog No.: PC-62461Not For Human Use, Lab Use Only.

Ipidacrine is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels.

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Biological Activity

Ipidacrine is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels.
Ipidacrine enhances not only choline, but also adrenaline, serotonin, histamine, and oxytocin effects on smooth muscle.

Physicochemical Properties

M.Wt 188.27
Formula C12H16N2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine

References

1. Nabeshima T, et al. Eur J Pharmacol. 1988 Sep 23;154(3):263-9.

2. Onodera K, et al. Nihon Shinkei Seishin Yakurigaku Zasshi. 1998 Apr;18(2):33-7.

3. Kojima J, et al. Gen Pharmacol. 1998 Aug;31(2):297-300.

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