Chemical Structure : Ipragliflozin
CAS No.: 761423-87-4
Catalog No.: PC-44115Not For Human Use, Lab Use Only.
Ipragliflozin (ASP1941) is a highly potent and selective SGLT2 inhibitor with IC50 of 14 nM for hSGLT2.
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Ipragliflozin (ASP1941) is a highly potent and selective SGLT2 inhibitor with IC50 of 14 nM for hSGLT2.
Ipragliflozin shows 254-fold selectivity over hSGLT1.
Ipragliflozin reduces blood glucose levels in a dose-dependent manner in diabetic models KK-A(y) mice and STZ rats.
M.Wt | 404.4518 | |
Formula | C21H21FO5S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
D-Glucitol, 1,5-anhydro-1-C-[3-(benzo[b]thien-2-ylmethyl)-4-fluorophenyl]-, (1S)- |
1. Imamura M, et al. Bioorg Med Chem. 2012 May 15;20(10):3263-79.
2. Tahara A, et al. J Pharmacol Sci. 2012;120(1):36-44.
3. Tahara A, et al. Eur J Pharmacol. 2013 Sep 5;715(1-3):246-55.
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