Irinotecan | Topo I inhibitor | Probechem Biochemicals

Chemical Structure : Irinotecan

CAS No.: 97682-44-5

Catalog No.: PC-23976Not For Human Use, Lab Use Only.

Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex.

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100 mg	$88	In stock
250 mg	$148	In stock
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Biological Activity

Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex.

M.Wt	586.69
Formula	C33H38N4O6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate

1. Morales C, et al. J Neurooncol. 2002 Feb;56(3):219-26.

2. Pavillard V, et al. Cancer Chemother Pharmacol. 2002 Apr;49(4):329-35. Epub 2002 Jan 30.