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Chemical Structure : Irosustat
CAS No.: 288628-05-7
Catalog No.: PC-61431Not For Human Use, Lab Use Only.
Irosustat (STX-64, BN-83495, Oristusane, 667-coumate) is an orally active, highly potent, irreversible, nonsteroidal inhibitor of steroid sulfatase (STS) with IC50 of 8 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $248 | In stock | |
| 50 mg | $428 | In stock | |
| 100 mg | $728 | In stock | |
| 500 mg | Get quote |
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Irosustat (STX-64, BN-83495, Oristusane, 667-coumate) is an orally active, highly potent, irreversible, nonsteroidal inhibitor of steroid sulfatase (STS) with IC50 of 8 nM; inhibits the production of locally active estrogens and so inhibit estrogen-dependent cell growth in tumor cells; inhibits estrone sulfate-stimulated growth of uteri in ovariectomized rats.
| M.Wt | 309.336 | |
| Formula | C14H15NO5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Sulfamic acid, 6,7,8,9,10,11-hexahydro-6-oxobenzo[b]cyclohepta[d]pyran-3-yl ester |
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1. Purohit A, et al. Cancer Res. 2000 Jul 1;60(13):3394-6.
2. Woo LL, et al. Chem Biol. 2000 Oct;7(10):773-91.
3. Stanway SJ, et al. Clin Cancer Res. 2006 Mar 1;12(5):1585-92.
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