Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Irresistin-16
Catalog No.: PC-22131Not For Human Use, Lab Use Only.
Irresistin-16 (IRS-16) is a potent bacterial dihydrofolate reductase (DHFR) inhibitor for purified E. coli DHFR (FolA), exhibits potent activity against S.aureus MRSA and N. gonorrhoeae with MIC of 1.56 and 0.03 ug/mL, respectively.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Irresistin-16 (IRS-16) is a potent bacterial dihydrofolate reductase (DHFR) inhibitor for purified E. coli DHFR (FolA), exhibits potent activity against S.aureus MRSA and N. gonorrhoeae with MIC of 1.56 and 0.03 ug/mL, respectively.
Irresistin-16 (IRS-16) (10 mg/kg, i.v., twice a day [b.i.d.]) reduces the vaginal burden of N. gonorrhoeae 24 h after inoculation in mice.
| M.Wt | 365.44 | |
| Formula | C23H19N5 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Martin JK 2nd, et al. Cell. 2020 Jun 25;181(7):1518-1532.e14.
2. Hu X, et al. Pathogens. 2022 Jan 6;11(1):70.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
