Catalog No.: PC-27915Not For Human Use, Lab Use Only.
Isoliensinine is a bisbenzylisoquinoline alkaloid extracted from Nelumbo nucifera Gaertn., triggers HCC cell apoptosis via inducing p65 dephosphorylation at Ser536 and inhibition of NF-κB.
Isoliensinine is a bisbenzylisoquinoline alkaloid extracted from Nelumbo nucifera Gaertn., triggers HCC cell apoptosis via inducing p65 dephosphorylation at Ser536 and inhibition of NF-κB. Isoliensinine promotes p65/PP2A interaction in vitro and in vivo. Isoliensinine directly impairs PP2A/I2PP2A interaction. Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation. Isoliensinine ameliorates postoperative neurocognitive disorder in aged mice by restoring hippocampal IGF-1 receptor signaling and suppressing oxidative stress and neuroinflammation.
