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Isoquercetin

Chemical Structure : Isoquercetin

CAS No.: 482-35-9

Isoquercetin (3-Glucosylquercetin)

Catalog No.: PC-62114Not For Human Use, Lab Use Only.

Isoquercetin is a flavonoid and 3-O-glucoside of quercetin that displays selective cytotoxicity to cancer cells, primarily by inducing apoptosis and cell cycle arrest, regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Isoquercetin is a flavonoid and 3-O-glucoside of quercetin that displays selective cytotoxicity to cancer cells, primarily by inducing apoptosis and cell cycle arrest, regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system.

Physicochemical Properties

M.Wt 464.379
Formula C21H20O12
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-[(3R,4R,5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-yl]oxy-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one

References

1. Huang XL, et al. Oncotarget. 2017 Sep 16;8(60):101545-101559.

2. Chen F, et al. Oncol Rep. 2016 Jul;36(1):165-72.

3. Zhu M, et al. Molecules. 2016 Mar 21;21(3):356.

4. Wu P, et al. Food Funct. 2017 Oct 18;8(10):3707-3722.

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