Itareparib (NMS-293, NMS-03305293) | PARP1 inhibitor

Chemical Structure : Itareparib

Itareparib (NMS-293, NMS-03305293, NMS293)

Catalog No.: PC-24140Not For Human Use, Lab Use Only.

Itareparib (NMS-293, NMS-03305293) is a potent, selective PARP-1 inhibitor with IC50 of <0.01 uM, shows potential for treatment of cancer, cardiovascular disease, central nervous system injury, and inflammation.

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Biological Activity

Itareparib (NMS-293, NMS-03305293) is a potent, selective PARP-1 inhibitor with IC50 of <0.01 uM, shows potential for treatment of cancer, cardiovascular disease, central nervous system injury, and inflammation.

Physicochemical Properties

M.Wt	359.45
Formula	C20H26FN3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(1-cyclohexylpiperidin-4-yl)-6-fluoro-3-oxoisoindoline-4-carboxamide

References

1. Patent WO2014064149 A1.

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Itareparib (NMS-293, NMS-03305293, NMS293)

Biological Activity

Physicochemical Properties

References

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