Ivabradine hydrochloride

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Chemical Structure : Ivabradine hydrochloride

CAS No.: 148849-67-6

Catalog No.: PC-22225Not For Human Use, Lab Use Only.

Ivabradine hydrochloride is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker, inhibits the cardiac pacemaker current (If).

Packing	Price	Stock
50 mg	$58	In stock
100 mg	$88	In stock
250 mg	$138	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Ivabradine hydrochloride is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker, inhibits the cardiac pacemaker current (If).

Physicochemical Properties

M.Wt	505.05
Formula	C27H37ClN2O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one hydrochloride

References

1. Tardif JC, et al. Eur Heart J. 2005 Dec;26(23):2529-36.

2. Du XJ, et al. Br J Pharmacol. 2004 May;142(1):107-12.

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