Chemical Structure : Ixabepilone
CAS No.: 219989-84-1
Catalog No.: PC-42466Not For Human Use, Lab Use Only.
A semisynthetic Epothilone B analogue and potent, orally active microtubule stabilizer.
Packing | Price | Stock | Quantity |
---|---|---|---|
10 mg | $352 | In stock | |
50 mg | $1200 | In stock | |
250 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
A semisynthetic Epothilone B analogue and potent, orally active microtubule stabilizer; shows a broad spectrum of activity against a panel of tumor cell lines in vitro (IC50=1.4-34.5 nM), retains the antineoplastic activity against human cancers that are resistance to paclitaxel both in vitro and in vivo.
Breast Cancer
Approved
M.Wt | 506.6978 | |
Formula | C27H42N2O5S | |
Appearance | Solid | |
Storage |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
17-Oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione, 7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-, (1S,3S,7S,10R,11S,12S,16R)- |
1. Lee FY, et al. Clin Cancer Res. 2001 May;7(5):1429-37.
2. Yamaguchi H, et al. Cancer Res. 2002 Jan 15;62(2):466-71.
3. Peterson JK, et al. Clin Cancer Res. 2005 Oct 1;11(19 Pt 1):6950-8.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright