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Chemical Structure : J8-C8
Catalog No.: PC-62035Not For Human Use, Lab Use Only.
J8-C8 is a small-molecule inhibitor of bacterial N-acyl-homoserine lactone synthase (acyl-HSLs) TofI with IC50 of 35 uM for toxoflavin production.
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J8-C8 is a small-molecule inhibitor of bacterial N-acyl-homoserine lactone synthase (acyl-HSLs) TofI with IC50 of 35 uM for toxoflavin production.
J8-C8 inhibits N-octanoyl-L-HSL (C8-HSL) synthesis in a dose-dependent manner.
J8-C8 is a new class of quorum sensing (QS)-inhibiting therapeutic agents.
| M.Wt | 237.343 | |
| Formula | C14H23NO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Chung J, et al. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12089-94.
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