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JBD1

Chemical Structure : JBD1

CAS No.: 577981-37-4

JBD1 (S. aureus biofilm inhibitor)

Catalog No.: PC-49157Not For Human Use, Lab Use Only.

JBD1 is a small molecule compound that strongly inhibits biofilm formation of S. aureus, including methicillin-resistant strains, induces biofilm inhibition and metabolic remodeling through respiratory activation.

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    Biological Activity

    JBD1 is a small molecule compound that strongly inhibits biofilm formation of S. aureus, including methicillin-resistant strains, induces biofilm inhibition and metabolic remodeling through respiratory activation.
    JBD1 activated the respiratory activity of S. aureus cells and increased the sensitivity to aminoglycosides.
    JBD1 altered the metabolic profile of S. aureus and induced metabolic remodeling.

    Physicochemical Properties

    M.Wt 349.475
    Formula C19H31N3O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (E)-3-cyclohexyl-5-(1-(hexylamino)propylidene)-6-hydroxypyrimidine-2,4(3H,5H)-dione

    References

    1. Ken-Ichi Okuda, et al. mBio. 2022 Jul 19;e0084522.

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