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Chemical Structure : JCP276
Catalog No.: PC-72860Not For Human Use, Lab Use Only.
JCP276 is a novel antibiotic and covalent inhibitor that disrupt M. tuberculosis growth by targeting multiple serine hydrolases.
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JCP276 is a novel antibiotic and covalent inhibitor that disrupt M. tuberculosis growth by targeting multiple serine hydrolases.
JCP276 is a narrow-spectrum inhibitor of Mycobacterium tuberculosis growth.
JCP276 inhibits multiple nonessential serine hydrolases.
JCP276 treatment caused accumulation of free lipids and a substantial decrease in lipooligosaccharides, linking SH inhibition to defects in cell envelope biogenesis.
| M.Wt | 451.70 | |
| Formula | C19H16BrClN2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Brett M Babin, et al. Cell Chem Biol. 2021 Sep 20;S2451-9456(21)00402-5.
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