JH-I-25

Chemical Structure : JH-I-25

Catalog No.: PC-22315Not For Human Use, Lab Use Only.

JH-I-25 is a potent, selective and orally bioavailable interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor with IC50 of 20 nM.

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Biological Activity

JH-I-25 is a potent, selective and orally bioavailable interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor with IC50 of 20 nM.

M.Wt	379.42
Formula	C20H21N5O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-methoxy-4-morpholinophenyl)-6-(1H-pyrazol-5-yl)picolinamide

1. George M Buckley, et al. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3211-4.