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JJ3297

Chemical Structure : JJ3297

CAS No.: 153810-66-3

JJ3297 (JJ 3297)

Catalog No.: PC-38714Not For Human Use, Lab Use Only.

JJ3297 is a potent antagonist of influenza virus non-structural protein 1 (NS1), strongly restores IFN-β mRNA levels and inhibits viral replication in MDCK cells (IC50=0.8 uM).

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Biological Activity

JJ3297 is a potent antagonist of influenza virus non-structural protein 1 (NS1), strongly restores IFN-β mRNA levels and inhibits viral replication in MDCK cells (IC50=0.8 uM).
JJ3297 inhibits influenza viral infection multi-cycle but not single-cycle infections, effectively inhibits the synthesis of IFN in infected cells.

Physicochemical Properties

M.Wt 255.317
Formula C16H17NO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-hydroxy-N-(3-phenylpropyl)benzamide

References

1. Walkiewicz MP, et al. J Gen Virol. 2011 Jan;92(Pt 1):60-70.

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