JMH021 | JNK3 inhibitor | Probechem Biochemicals

You are here:Home-Chemical Inhibitors & Agonists-Ras-Raf-MAPK-ERK Pathway-JNK-JMH021

Chemical Structure : JMH021

JMH021 (JMH-021)

Catalog No.: PC-26256Not For Human Use, Lab Use Only.

JMH021 is a potent, isoform-selective JNK3 inhibitor with IC50 of 2.0 nM, 30- to 150-fold greater potency against JNK3 compared to JNK1 or JNK2.

Packing	Price	Stock	Quantity
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

JMH021 is a potent, isoform-selective JNK3 inhibitor with IC50 of 2.0 nM, 30- to 150-fold greater potency against JNK3 compared to JNK1 or JNK2.
JMH021 demonstrated that it effectively alleviated TGF-β1-induced podocyte injury.

Physicochemical Properties

M.Wt	496.40
Formula	C24H23Cl2N7O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-(1-(2-((1-(cyclopropanecarbonyl)piperidin-3-yl)amino)pyrimidin-4-yl)-2-(3,4-dichlorophenyl)-1H-imidazole-5-yl)acetonitrile

References

1. Joonhong Jun, et al. Eur J Med Chem. 2023 Jan 5;245(Pt 1):114894.

2. Joonhong Jun, et al. J Med Chem. 2026 Feb 12;69(3):3077-3099.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

JMH021 (JMH-021)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.