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JMN3-003

Chemical Structure : JMN3-003

CAS No.: 1331868-55-3

JMN3-003 (JMN 3-003)

Catalog No.: PC-73389Not For Human Use, Lab Use Only.

JMN3-003 is a host-directed inhibitor with potent antiviral activity against a panel of myxovirus family members with EC50 of 10-70 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    JMN3-003 is a host-directed inhibitor with potent antiviral activity against a panel of myxovirus family members with EC50 of 10-70 nM.
    JMN3-003 shows activity against MeV at 170 (viral CPE-reduction assay) and 30 nM (virus yield reduction assay) and does not display any detectable acute cytotoxicity.
    JMN3-003 also shows superb antiviral activity against a selection of clinical-relevant paramyxovirus (RSV, MuV, and HPIV3) and orthomyxovirus (influenza) family members.

    Physicochemical Properties

    M.Wt 451.969
    Formula C24H22ClN3O2S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(2-chloro-4-methylphenyl)-2-((1-(4-methoxyphenyl)-1H-benzo[d]imidazol-2-yl)thio)propanamide

    References

    1. Sun A, et al. ACS Med Chem Lett. 2011 Aug 23;2(11):798-803.

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