Chemical Structure : JMN3-003
Catalog No.: PC-73389Not For Human Use, Lab Use Only.
JMN3-003 is a host-directed inhibitor with potent antiviral activity against a panel of myxovirus family members with EC50 of 10-70 nM.
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JMN3-003 is a host-directed inhibitor with potent antiviral activity against a panel of myxovirus family members with EC50 of 10-70 nM.
JMN3-003 shows activity against MeV at 170 (viral CPE-reduction assay) and 30 nM (virus yield reduction assay) and does not display any detectable acute cytotoxicity.
JMN3-003 also shows superb antiviral activity against a selection of clinical-relevant paramyxovirus (RSV, MuV, and HPIV3) and orthomyxovirus (influenza) family members.
M.Wt | 451.969 | |
Formula | C24H22ClN3O2S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Sun A, et al. ACS Med Chem Lett. 2011 Aug 23;2(11):798-803.
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