Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
EN | CN

You are here:Home-Chemical Inhibitors & Agonists-GPCR-Ghrelin Receptor (GHSR)-JMV 2959
JMV 2959

Chemical Structure : JMV 2959

CAS No.: 925238-89-7

JMV 2959 (JMV-2959, AEZS-123)

Catalog No.: PC-61828Not For Human Use, Lab Use Only.

JMV 2959 (AEZS-123) is a potent ghrelin receptor (GHS-R1A) antaognist with binding IC50 of 32 nM.

Packing Price Stock Quantity
5 mg $128 In stock
10 mg $198 In stock
25 mg $348 In stock
50 mg $548 In stock
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

JMV 2959 (JMV-2959, AEZS-123) is a potent ghrelin receptor (GHS-R1A) antaognist with binding IC50 of 32 nM.
JMV 2959 suppresses ghrelin-induced and fasting-induced food intake at the level of the central nervous system.
JMV 2959 attenuates the NMDAR antagonist, phencyclidine-induced impairments in prepulse inhibition in rats.

Physicochemical Properties

M.Wt 508.626
Formula C30H32N6O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-Amino-N-[(1R)-2-(1H-indol-3-yl)-1-[4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl]ethyl]acetamide

References

1. Salomé N, et al. Eur J Pharmacol. 2009 Jun 10;612(1-3):167-73.

2. Landgren S, et al. Addict Biol. 2012 Jan;17(1):86-94.

3. Engel JA, et al. Psychopharmacology (Berl). 2015 Dec;232(23):4285-92.

4. Moulin A, et al. Amino Acids. 2013 Feb;44(2):301-14.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: