Chemical Structure : JMV 2959
CAS No.: 925238-89-7
Catalog No.: PC-61828Not For Human Use, Lab Use Only.
JMV 2959 (AEZS-123) is a potent ghrelin receptor (GHS-R1A) antaognist with binding IC50 of 32 nM.
Packing | Price | Stock | Quantity |
---|---|---|---|
5 mg | $128 | In stock | |
10 mg | $198 | In stock | |
25 mg | $348 | In stock | |
50 mg | $548 | In stock | |
100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
JMV 2959 (JMV-2959, AEZS-123) is a potent ghrelin receptor (GHS-R1A) antaognist with binding IC50 of 32 nM.
JMV 2959 suppresses ghrelin-induced and fasting-induced food intake at the level of the central nervous system.
JMV 2959 attenuates the NMDAR antagonist, phencyclidine-induced impairments in prepulse inhibition in rats.
M.Wt | 508.626 | |
Formula | C30H32N6O2 | |
Appearance | Solid | |
Storage |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
2-Amino-N-[(1R)-2-(1H-indol-3-yl)-1-[4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl]ethyl]acetamide |
1. Salomé N, et al. Eur J Pharmacol. 2009 Jun 10;612(1-3):167-73.
2. Landgren S, et al. Addict Biol. 2012 Jan;17(1):86-94.
3. Engel JA, et al. Psychopharmacology (Berl). 2015 Dec;232(23):4285-92.
4. Moulin A, et al. Amino Acids. 2013 Feb;44(2):301-14.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright