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Chemical Structure : JMV449
CAS No.: 139026-66-7
Catalog No.: PC-20496Not For Human Use, Lab Use Only.
JMV449 (JMV-449) is a potent, metabolically stable neurotensin receptor agonist peptide with IC50 of 0.15 nM for inhibition of [125I]-NT binding to neonatal mouse brain.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $498 | In stock | |
| 10 mg | $758 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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JMV449 (JMV-449) is a potent, metabolically stable neurotensin receptor agonist peptide with IC50 of 0.15 nM for inhibition of [125I]-NT binding to neonatal mouse brain.
JMV449 produces long-lasting hypothermic, neuroprotective and analgesic effects in mice following central administration in vivo.
| M.Wt | 746.96 | |
| Formula | C38H66N8O7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
[H]N[C@@H](CCCCN)CN[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(O)=O |
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1. D Lugrin, et al. Eur J Pharmacol. 1991 Nov 26;205(2):191-8.
2. I Dubuc, et al. Eur J Pharmacol. 1992 Aug 25;219(2):327-9.
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