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Chemical Structure : JNJ-10311795
Catalog No.: PC-22251Not For Human Use, Lab Use Only.
JNJ-10311795 is a potent dual inhibitor of neutrophil cathepsin G (Ki=38 nM) and mast cell chymase (Ki=2.3 nM), exhibits noteworthy anti-inflammatory activity in rats for glycogen-induced peritonitis and LPS-induced airway inflammation.
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JNJ-10311795 is a potent dual inhibitor of neutrophil cathepsin G (Ki=38 nM) and mast cell chymase (Ki=2.3 nM), exhibits noteworthy anti-inflammatory activity in rats for glycogen-induced peritonitis and LPS-induced airway inflammation.
| M.Wt | 670.70 | |
| Formula | C40H35N2O6P | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Tausch L, et al. J Immunol. 2009 Sep 1;183(5):3433-42.
2. de Garavilla L, et al. J Biol Chem. 2005 May 6;280(18):18001-7.
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