JNJ-40279486 |CAS:1002351-34-9 Probechem Biochemicals

Chemical Structure : JNJ-40279486

JNJ-40279486 (JNJ40279486)

Catalog No.: PC-63417Not For Human Use, Lab Use Only.

JNJ-40279486 is a potent, selective histamine H4 receptor antagonist with Ki of 9.4 nM (hH4), demonstrates acceptable pharmacokinetic profile and efficacy in mouse model of inflammation..

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Biological Activity

JNJ-40279486 is a potent, selective histamine H4 receptor antagonist with Ki of 9.4 nM (hH4), demonstrates acceptable pharmacokinetic profile and efficacy in mouse model of inflammation.

Physicochemical Properties

M.Wt	318.765
Formula	C14H15ClN6O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-8-chloro-4-(3-(methylamino)pyrrolidin-1-yl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-amine

References

1. Savall BM, et al. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6577-81.

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JNJ-40279486 (JNJ40279486)

Biological Activity

Physicochemical Properties

References

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