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Chemical Structure : JNJ-40929837
Catalog No.: PC-72652Not For Human Use, Lab Use Only.
JNJ-40929837 (JNJ40929837) is a potent, highly selective, oral leukotriene A4 hydrolase (LTA4H) inhibitor with IC50 of 1.9 nM, demonstrates high potency (IC50=48 nM) in human whole blood ionophore-stimulated LTB4 release assay.
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JNJ-40929837 (JNJ40929837) is a potent, highly selective, oral leukotriene A4 hydrolase (LTA4H) inhibitor with IC50 of 1.9 nM, demonstrates high potency (IC50=48 nM) in human whole blood ionophore-stimulated LTB4 release assay.
| M.Wt | 408.52 | |
| Formula | C22H24N4O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Barchuk W, et al. Pulm Pharmacol Ther. 2014 Oct;29(1):15-23.
2. Christian Markert, et al. J Med Chem. 2021 Feb 25;64(4):1889-1903.
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