Catalog No.: PC-61493Not For Human Use, Lab Use Only.
JNJ-53718678 (JNJ53718678, JNJ-678) is a potent (Kd=7.4 nM), small-molecule inhibitor of the F-glycoprotein-mediated complex membrane fusion process of the RSV.
JNJ-53718678 (JNJ53718678, JNJ-678) is a potent (Kd=7.4 nM), small-molecule inhibitor of the F-glycoprotein-mediated complex membrane fusion process of the RSV.
JNJ-53718678 displays very potent antiviral activity and low cytotoxicity.
JNJ-53718678 inhibits ESV replication in HBECs with IC50 of 1.2 nM, efficiently inhibits RSV infection in vivo.
