JNJ-56022486 | TARP-γ8 modulator | Probechem Biochemicals

Chemical Structure : JNJ-56022486

JNJ-56022486 (JNJ56022486)

Catalog No.: PC-28480Not For Human Use, Lab Use Only.

JNJ-56022486 is a potent, selective and orally active negative AMPA receptor modulator with Ki of 18 nM for transmembrane AMPA receptor regulatory protein γ8 (TARP-γ8, CACNG8).

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Biological Activity

JNJ-56022486 is a potent, selective and orally active negative AMPA receptor modulator with Ki of 18 nM for transmembrane AMPA receptor regulatory protein γ8 (TARP-γ8, CACNG8).

Physicochemical Properties

M.Wt	283.72
Formula	C15H10ClN3O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3-chloro-2-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)phenyl)acetonitrile

References

1. Maher MP, et al. J Pharmacol Exp Ther. 2016 May;357(2):394-414.

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JNJ-56022486 (JNJ56022486)

Biological Activity

Physicochemical Properties

References

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