JNJ19567470 | CRF1 antagonist | Probechem Biochemicals

Chemical Structure : JNJ19567470

JNJ19567470 (R317573, CRA5626, JNJ-19567470)

Catalog No.: PC-27084Not For Human Use, Lab Use Only.

JNJ19567470 (JNJ-19567470, R317573, CRA5626) is a potent, selective, non-peptide CRF receptor 1 (CRF1, CRFR1) antagonist, prevents sodium lactate-induced acute panic-like responses.

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Biological Activity

JNJ19567470 (JNJ-19567470, R317573, CRA5626) is a potent, selective, non-peptide CRF receptor 1 (CRF1, CRFR1) antagonist, prevents sodium lactate-induced acute panic-like responses.

Physicochemical Properties

M.Wt	443.39
Formula	C22H27BrN4O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(1-(7-(4-bromo-2,6-dimethylphenyl)-2,5-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl)methanol

References

1. Anantha Shekhar, et al. Int J Neuropsychopharmacol. 2011 Apr;14(3):355-65.

2. Zhou J, et al. Regul Toxicol Pharmacol. 2025 Sep;161 Suppl 1:105334.

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JNJ19567470 (R317573, CRA5626, JNJ-19567470)

Biological Activity

Physicochemical Properties

References

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