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Chemical Structure : JNJ525
Catalog No.: PC-62163Not For Human Use, Lab Use Only.
JNJ525 is a small molecule inhibitor of TNFα that prevents the formation of TNFα complexes with TNFR1 and TNFR2 with IC50 of 1.2 uM and 1.1 uM in the TR-FRET assay, respectively.
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JNJ525 is a small molecule inhibitor of TNFα that prevents the formation of TNFα complexes with TNFR1 and TNFR2 with IC50 of 1.2 uM and 1.1 uM in the TR-FRET assay, respectively.
| M.Wt | 514.637 | |
| Formula | C31H30N8 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Blevitt JM, et al. J Med Chem. 2017 Apr 27;60(8):3511-3517.
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