Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Apoptosis-TNF-alpha-JNJ525
JNJ525

Chemical Structure : JNJ525

CAS No.: 2092913-64-7

JNJ525 (JNJ 525, JNJ-525)

Catalog No.: PC-62163Not For Human Use, Lab Use Only.

JNJ525 is a small molecule inhibitor of TNFα that prevents the formation of TNFα complexes with TNFR1 and TNFR2 with IC50 of 1.2 uM and 1.1 uM in the TR-FRET assay, respectively.

Packing Price Stock Quantity
50 mg Get quote
100 mg Get quote
250 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    JNJ525 is a small molecule inhibitor of TNFα that prevents the formation of TNFα complexes with TNFR1 and TNFR2 with IC50 of 1.2 uM and 1.1 uM in the TR-FRET assay, respectively.

    Physicochemical Properties

    M.Wt 514.637
    Formula C31H30N8
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N4-benzyl-N4-(3'-(2-(piperazin-1-yl)pyrimidin-5-yl)-[1,1'-biphenyl]-2-yl)pyrimidine-2,4-diamine

    References

    1. Blevitt JM, et al. J Med Chem. 2017 Apr 27;60(8):3511-3517.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: