Chemical Structure : JNK3 inhibitor JC16I
CAS No.: 3079739-71-9
Catalog No.: PC-23102Not For Human Use, Lab Use Only.
JNK3 inhibitor JC16I is a potent, selective covalent JNK3 inhibitor with IC50 of 5.31 nM, >160-fold selectivity for JNK3 over JNK1/2.
Packing | Price | Stock | Quantity |
---|---|---|---|
2 mg | $198 | In stock | |
5 mg | $328 | In stock | |
10 mg | $528 | In stock | |
50 mg | Get quote | ||
100 mg | Get quote |
Bulk size, bulk discount!
Welcome credit card payment!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
JNK3 inhibitor JC16I is a potent, selective covalent JNK3 inhibitor with IC50 of 5.31 nM, >160-fold selectivity for JNK3 over JNK1/2.
JC16I showed enhanced and long-lasting inhibition against cellular JNK3.
JC16I selectively suppressed the abnormal activation of JNK3 signaling and sufficiently exhibited neuroprotective effect in Parkinson's diseases (PD) models.
M.Wt | 577.47 | |
Formula | C29H26Cl2N6O3 | |
Appearance | Solid | |
Storage |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
N-(2-chloro-5-(4-(4-(((4-chloro-1H-indazol-3-yl)amino)methyl)benzoyl)piperazine-1-carbonyl)phenyl)acrylamide |
1. Liang Ouyang, et al. Angew Chem Int Ed Engl. 2024 Sep 14:e202411037.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright