JP-III-48 |CAS: 1859112-10-9 Probechem Biochemicals

Chemical Structure : JP-III-48

Catalog No.: PC-70319Not For Human Use, Lab Use Only.

JP-III-48 is a small molecule CD4-mimetic that binds gp120 and blocks CD4 binding, inhibits HIV-1 entry.

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Biological Activity

JP-III-48 is a small molecule CD4-mimetic that binds gp120 and blocks CD4 binding, inhibits HIV-1 entry.

M.Wt	446.91
Formula	C21H24ClFN6O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N1-(4-chloro-3-fluorophenyl)-N2-((1R,2R)-2-(guanidinomethyl)-6-((methylamino)methyl)-2,3-dihydro-1H-inden-1-yl)oxalamide

1. Madani N, et al. Structure. 2008 Nov 12; 16(11):1689-701.

2. Richard J, et al. Proc Natl Acad Sci U S A. 2015 May 19;112(20):E2687-94.