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Chemical Structure : JRC-II-191
Catalog No.: PC-22327Not For Human Use, Lab Use Only.
JRC-II-191 is a small-molecule CD4 mimic with Kd of 760 nM for gp120 envelope glycoprotein, inhibits HIV-1 entry by blocking the binding of the HIV-1 envelope glycoprotein gp120 to the CD4 receptor.
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JRC-II-191 is a small-molecule CD4 mimic with Kd of 760 nM for gp120 envelope glycoprotein, inhibits HIV-1 entry by blocking the binding of the HIV-1 envelope glycoprotein gp120 to the CD4 receptor.
| M.Wt | 355.84 | |
| Formula | C17H23ClFN3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Haim H, et al. PLoS Pathog. 2009 Apr;5(4):e1000360.
2. Madani N, et al. Structure. 2008;16:1689–1701.
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