JSF-4536 | M.tb MenG inhibitor | Probechem Biochemicals

Chemical Structure : JSF-4536

JSF-4536 (JSF4536)

Catalog No.: PC-24466Not For Human Use, Lab Use Only.

JSF-4536 is a small molecule inhibitor of Mycobacterium tuberculosis methyltransferase MenG enzyme, inhibits menaquinone biosynthetic pathway, inhibits M. tuberculosis H37Rv strain with MIC of 0.78 uM.

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Biological Activity

Physicochemical Properties

M.Wt	416.88
Formula	C22H22ClFN2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5′-(2-Chloro-4-fluorobenzamido)-2′-methoxy-N-methyl-2,3,4,5-tetrahydro-[1,1′-biphenyl]-4-carboxamide

References

1. Pankaj Sharma, et al. J Med Chem. 2025 Mar 13;68(5):5774-5803.

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JSF-4536 (JSF4536)

Biological Activity

Physicochemical Properties

References

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