JVW-1009 |CAS:2089059-30-1 Probechem Biochemicals

Chemical Structure : JVW-1009

JVW-1009 (JVW 1009;JVW1009)

Catalog No.: PC-61101Not For Human Use, Lab Use Only.

A small molecule sigma receptor ligand with Ki of 96 and 70 nM for sigma 1 and sigma 2, respectively.

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Biological Activity

JVW-1009 is a small molecule sigma receptor ligand with Ki of 96 and 70 nM for sigma 1 and sigma 2, respectively.
JVW-1009 reduces neurodegeneration in C. elegans model of amyloid precursor protein-mediated neurodegeneration.

Physicochemical Properties

M.Wt	340.47
Formula	C24H24N2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(1R,5R)-2-benzyl-N-phenyl-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[c]azepin-8-amine

References

1. Yi B, et al. J Neurochem. 2017 Feb;140(4):561-575.

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JVW-1009 (JVW 1009;JVW1009)

Biological Activity

Physicochemical Properties

References

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