Chemical Structure : JW 642
CAS No.: 1416133-89-5
Catalog No.: PC-42980Not For Human Use, Lab Use Only.
JW 642 (JW642) is a potent, selective monoacylglycerol lipase (MAGL) inhibitor with IC50 of 7.6, 14 and 3.7 nM for mouse, rat and human MAGL, respectively.
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JW 642 (JW642) is a potent, selective monoacylglycerol lipase (MAGL) inhibitor with IC50 of 7.6, 14 and 3.7 nM for mouse, rat and human MAGL, respectively.
JW 642 display little to no activity against human FAAH (IC50>20 uM).
M.Wt | 462.3855 | |
Formula | C21H20F6N2O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
1-Piperazinecarboxylic acid, 4-[(3-phenoxyphenyl)methyl]-, 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ester |
1. Chang JW, et al. Chem Biol. 2012 May 25;19(5):579-88.
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