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Chemical Structure : JW 642
Catalog No.: PC-42980Not For Human Use, Lab Use Only.
JW 642 (JW642) is a potent, selective monoacylglycerol lipase (MAGL) inhibitor with IC50 of 7.6, 14 and 3.7 nM for mouse, rat and human MAGL, respectively.
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JW 642 (JW642) is a potent, selective monoacylglycerol lipase (MAGL) inhibitor with IC50 of 7.6, 14 and 3.7 nM for mouse, rat and human MAGL, respectively; display little to no activity against human FAAH (IC50>20 uM).
| M.Wt | 462.3855 | |
| Formula | C21H20F6N2O3 | |
| Appearance | Solid | |
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| Solubility |
10 mM in DMSO |
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1. Chang JW, et al. Chem Biol. 2012 May 25;19(5):579-88.
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