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Chemical Structure : JWD-065
Catalog No.: PC-73292Not For Human Use, Lab Use Only.
JWD-065 is a potent small molecule HIPK2 kinase inhibitor, blocks HIPK2 phosphorylation on S359/T360 and JNK activation in HEK293 cells and attenuates ER stress-induced cell death with EC50 of 641 nM.
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JWD-065 is a potent small molecule HIPK2 kinase inhibitor, blocks HIPK2 phosphorylation on S359/T360 and JNK activation in HEK293 cells and attenuates ER stress-induced cell death with EC50 of 641 nM.
| M.Wt | 462.572 | |
| Formula | C24H26N6O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Sebum Lee, et al. Neuron. 2016, 91(1), 41-55.
2. Miduturu CV et al. Chem Biol. 2011;18:868–879.
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