JX-7 | NNRTI | Probechem Biochemicals

Chemical Structure : JX-7

JX-7 (NNRTI inhibitor)

Catalog No.: PC-38800Not For Human Use, Lab Use Only.

JX-7 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) with remarkable inhibitory activity against wild-type HIV-1 (EC50=5 nM) and numerous clinically observed variants in MT-4 cells.

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Biological Activity

JX-7 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) with remarkable inhibitory activity against wild-type HIV-1 (EC50=5 nM) and numerous clinically observed variants in MT-4 cells.

Physicochemical Properties

M.Wt	438.447
Formula	C24H18N6O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	6-((6-amino-2-((4-cyanophenyl)amino)pyrimidin-4-yl)oxy)-5,7-dimethoxy-2-naphthonitrile

References

1. Xin Jin, et al. J Med Chem. 2022 Jun 1. doi: 10.1021/acs.jmedchem.2c00468.

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JX-7 (NNRTI inhibitor)

Biological Activity

Physicochemical Properties

References

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