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K-8794

Chemical Structure : K-8794

CAS No.: 180577-26-8

K-8794 (K8794)

Catalog No.: PC-28490Not For Human Use, Lab Use Only.

K-8794 is a potent, selective and orally active selective endothelin-B-(ETB) receptor antagonist.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

K-8794 is a potent, selective and orally active selective endothelin-B-(ETB) receptor antagonist.

Physicochemical Properties

M.Wt 682.80
Formula C36H38N6O6S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-((6-((4-(tert-butyl)phenyl)sulfonamido)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)oxy)-N-(2,6-dimethylphenyl)propanamide

References

1. Sawaki M, et al. J Cardiovasc Pharmacol. 2000 Nov;36(5 Suppl 1):S323-6.

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