Chemical Structure : K252a
CAS No.:
99533-80-9
K252a
(SF-2370;K 252a; SF2370)
Catalog No. : PC-70171Not For Human Use, Lab Use Only.
K252a (SF2370) is a potent, non-selective tyrosine protein kinase inhibitor for Trk family, CaMK and other phosphorylase kinases.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-7017101
Biological Activity
K252a (SF2370) is a potent, non-selective tyrosine protein kinase inhibitor for Trk family , CaMK and other phosphorylase kinases.
Physicochemical Properties
M.Wt
467.5
Formula
C27H21N3O5
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
methyl (5R,7R,8S)-7-hydroxy-15-oxo-5,6,7,8,14,15-hexahydro-13H-16-oxa-4b,8a,14-triaza-5,8-methanodibenzo[b,h]cycloocta[jkl]cyclopenta[e]-as-indacene-7-carboxylate
References
1. Morotti A, et al. Oncogene.
2. Ruggeri BA, et al. Curr Med Chem.
3. Tapley P, et al. Oncogene.
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